{"abstracts":[{"sha1":"228e0c080e76865d309dd918941cba2ee8643f71","content":"ABSTRACT\nMarine actinomycetes (order Actinomycetales) are of interest as a promising source of pharmaceuticals. The genomes of three novel sponge-associated actinomycetes exhibiting antimycobacterial activity, Brevibacterium sp. strain XM4083, Micrococcus sp. strain R8502A1, and Micromonospora sp. strain XM-20-01, were sequenced in an effort to identify compounds responsible for growth-inhibiting activity.","mimetype":"application/xml+jats"}],"refs":[{"index":0,"extra":{"authors":["Bérdy"],"doi":"10.1038/ja.2005.1","volume":"58"},"key":"B1","year":2005,"container_name":"J Antibiot","title":"Bioactive microbial metabolites"},{"index":1,"extra":{"authors":["Genilloud"],"doi":"10.3390/antibiotics7040085"},"key":"B2","year":2018,"container_name":"Antibiotics","title":"Mining actinomycetes for novel antibiotics in the omics era: are we ready to exploit this new paradigm?","locator":"85"},{"index":2,"extra":{"authors":["Hug"],"doi":"10.3390/antibiotics7020044"},"key":"B3","year":2018,"container_name":"Antibiotics","title":"Concepts and methods to access novel antibiotics from actinomycetes","locator":"44"},{"index":3,"extra":{"authors":["Fenical"],"doi":"10.1038/nchembio841"},"key":"B4","year":2006,"container_name":"Nat Chem Biol","title":"Developing a new resource for drug discovery: marine actinomycete bacteria","locator":"666"},{"index":4,"extra":{"authors":["Solecka"],"doi":"10.2478/s11535-012-0036-1"},"key":"B5","year":2012,"container_name":"Cent Eur J Biol","title":"Biologically active secondary metabolites from actinomycetes","locator":"373"},{"index":5,"extra":{"authors":["Talukdar"],"doi":"10.1016/j.gene.2016.09.005","volume":"594"},"key":"B6","year":2016,"container_name":"Gene","title":"Complete genome sequencing and comparative analysis of broad-spectrum antimicrobial-producing Micromonospora sp. HK10","locator":"97"},{"index":6,"extra":{"authors":["Carlson"],"doi":"10.3390/md11041152","volume":"11"},"key":"B7","year":2013,"container_name":"Mar Drugs","title":"Potential chemopreventive activity of a new macrolide antibiotic from a marine-derived Micromonospora sp","locator":"1152"},{"index":7,"extra":{"authors":["Carro"],"doi":"10.1038/s41598-017-17392-0"},"key":"B8","year":2018,"container_name":"Sci Rep","title":"Genome-based classification of micromonosporae with a focus on their biotechnological and ecological potential","locator":"525"},{"index":8,"extra":{"authors":["Motta"],"doi":"10.1046/j.1365-2672.2002.01490.x","volume":"92"},"key":"B9","year":2002,"container_name":"J Appl Microbiol","title":"Characterization of an antibacterial peptide produced by Brevibacterium linens","locator":"63"},{"index":9,"extra":{"authors":["Choi"],"doi":"10.1038/ja.2009.92","volume":"62"},"key":"B10","year":2009,"container_name":"J Antibiot","title":"6-Hydroxymethyl-1-phenazine-carboxamide and 1,6-phenazinedimethanol from a marine bacterium, Brevibacterium sp. KMD 003, associated with marine purple vase sponge","locator":"621"},{"index":10,"extra":{"authors":["Ramalingam"],"doi":"10.1016/j.procbio.2019.01.002","volume":"78"},"key":"B11","year":2019,"container_name":"Process Biochem","title":"Production and structure elucidation of anticancer potential surfactin from marine actinomycete Micromonospora marina","locator":"169"},{"index":11,"extra":{"authors":["Braesel"],"doi":"10.1021/acs.jnatprod.8b00394","volume":"81"},"key":"B12","year":2018,"container_name":"J Nat Prod","title":"Complete genome of Micromonospora sp. strain B006 reveals biosynthetic potential of a Lake Michigan actinomycete","locator":"2057"},{"index":12,"extra":{"authors":["Montalvo"],"doi":"10.1007/s10482-004-6536-x","volume":"87"},"key":"B13","year":2005,"container_name":"Antonie Van Leeuwenhoek","title":"Novel actinobacteria from marine sponges","locator":"29"},{"index":13,"extra":{"authors":["Bankevich"],"doi":"10.1089/cmb.2012.0021","volume":"19"},"key":"B14","year":2012,"container_name":"J Comput Biol","title":"SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing","locator":"455"},{"index":14,"extra":{"authors":["Wattam"],"doi":"10.1093/nar/gkw1017","volume":"45"},"key":"B15","year":2017,"container_name":"Nucleic Acids Res","title":"Improvements to PATRIC, the all-bacterial bioinformatics database and analysis resource center","locator":"D535"},{"index":15,"extra":{"authors":["Blin"],"doi":"10.1093/nar/gkx319","volume":"45"},"key":"B16","year":2017,"container_name":"Nucleic Acids Res","title":"antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification","locator":"W36"}],"contribs":[{"index":0,"raw_name":"Daniela Tizabi","given_name":"Daniela","surname":"Tizabi","role":"author","extra":{"seq":"first"}},{"index":1,"raw_name":"Ana Sosa","given_name":"Ana","surname":"Sosa","role":"author"},{"index":2,"raw_name":"Tsvetan Bachvaroff","given_name":"Tsvetan","surname":"Bachvaroff","role":"author"},{"index":3,"raw_name":"Russell T. Hill","given_name":"Russell T.","surname":"Hill","role":"author"},{"raw_name":"Frank J. 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